Suche


Prof. Dr. Jutta Eichler

Department Chemie and Pharmazie
Professur für Pharmazeutische Chemie
Schuhstr. 19
91052 Erlangen

Tel. 09131-85-24117
Fax: 09131-85-22587

jutta.eichler@fau.de
www.medchem.uni-erlangen.de

Research areas:

The general subject of our research is the exploration of protein-ligand interactions using synthetic peptides and peptidomimetics, with the aim to modulate protein function through controlled interference with the underlying molecular interactions. This involves the sructure-based design and generation of synthetic mimetics of structurally complex protein binding sites. We have established a repertoire of methods to design and synthesize such binding site mimetics, which we are now using to develop inhibitors of biomedically relevant protein-ligand interactions. Our projects focus on interactions of a range of proteins, including viral surface proteins, protein interaction domains, as well as cytokines and enzymes.